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Invitrogen™ IL-10 Monoclonal Antibody (CC320)
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Catalog No. PIMA516619
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500 μg
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Catalog No. Quantity
PIMA516619 500 μg
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Catalog No. PIMA516619 Supplier Invitrogen™ Supplier No. MA516619
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Description

Mouse Monoclonal Antibody

Membrane permeabilization is required for flow cytometry applications. This product is a low-endotoxin, preservative-free formulation. Endotoxin level is <0.01 EU/ug.

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
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Specifications

Antigen IL-10
Applications ELISA, Flow Cytometry, Functional Assay
Classification Monoclonal
Clone CC320
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene IL10
Gene Accession No. P43480, Q28374, Q29408
Gene Alias CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
Gene Symbols IL10
Host Species Mouse
Immunogen Plasmid cDNA encoding bovine IL-10.
Purification Method Protein A
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100034187, 100860746, 281246, 443342
Target Species Bovine, Sheep, Horse, Goat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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