IL-12 beta Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0950	100 μL

Catalog No. 50-198-0950 Supplier Bioss Supplier No. BS10641R

Description

Rabbit Polyclonal Antibody

IL12B (IL-12 p40) encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kDa cytokine receptor like subunit encoded by this gene, and a 35 kDa subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.

Specifications

• Antigen: IL-12 beta
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Il12b
• Gene Accession No.: P29460
• Gene Alias: CLMF; CLMF p35; CLMF p40; CLMF2; Cytotoxic lymphocyte maturation factor 40 kDa subunit; Il12; IL-12 p40 subunit; IL-12 subunit p35; IL-12 subunit p40; IL12, subunit p40; IL-12.p40; IL12A; IL-12A; IL12B; IL-12B; Il12p40; Il-12p40; ILN; IMD28; IMD29; Interleukin; Interleukin 12; interleukin 12 p40 subunit; interleukin 12, p40; interleukin 12B; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); Interleukin12; interleukin-12 beta chain; interleukin-12 p40; interleukin-12 p40 chain; interleukin-12 p40 subunit; Interleukin-12 subunit beta; interleukin-12p40; natural killer cell stimulatory factor, 40 kD subunit; NK cell stimulatory factor chain 2; NKSF; NKSF1; NKSF2; p40; RP23-388G23.1
• Gene Symbols: Il12b
• Host Species: Rabbit
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3593
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG