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Invitrogen™ IL-12 p35 Monoclonal Antibody (C1)
Mouse Monoclonal Antibody
$213.50 - $522.50
Specifications
Antigen | IL-12 p35 |
---|---|
Clone | C1 |
Concentration | 1 mg/mL |
Content And Storage | -20°C |
Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
PIMA541614
|
Invitrogen™
MA541614 |
200 μL |
Each for $522.50
|
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PIMA543742
|
Invitrogen™
MA543742 |
20 μL |
Each for $213.50
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Description
IL-12 p35 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)
Interleukin 12A is a novel signaling cytokine belonging to the Interleukin-6 protein superfamily. Interleukin-12 alpha chain precursor (IL-12A) is a 35-kD subunit of disulfide-linked heterodimer of cytokine IL-12 and has a broad array of biological activities. Reports suggest that IL-12A can act as a growth factor for activated T and NK cells and enhance the lytic activity of NK/lymphokine-activated Killer cells. IL-12A stimulates the production of IFN-gamma by resting PBMC as well as T-cell-independent induction of interferon (IFN)-gamma, and helps in the differentiation of both Th1 and Th2 cells. It is also involved in positive regulation of tyrosine phosphorylation of Stat4 protein. The signaling process of IL-12A in innate immunity requires nitric oxide synthase 2A. Along with EBI3, IL-12A forms a novel heterodimeric cytokine, designated as interleukin-35 (IL-35), that may be specifically produced by T reg cells and is required for maximal suppressive activity.Specifications
IL-12 p35 | |
1 mg/mL | |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
Unconjugated | |
Mouse | |
RUO | |
PBS with 50% glycerol and 0.05% ProClin 300 | |
P29459 | |
3592 | |
Recombinant protein Interleukin 12A. The antigen corresponds to amino acid range 23-219 of the target protein. | |
Antibody |
C1 | |
-20°C | |
Monoclonal | |
Liquid | |
IgG2b κ | |
Human | |
IL12A | |
CLMF; CLMF p35; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; il 12; IL-12 subunit p35; IL-12, subunit p35; Il12a; IL-12A; IL12p35; IL-12p35; IL35 subunit; ILN; Interleukin; Interleukin 12; interleukin 12 p35 subunit; interleukin 12, p35; interleukin 12a; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); Interleukin12; interleukin-12 alpha chain; interleukin-12 beta p35 subunit; interleukin-12 p35 subunit; interleukin-12 subunit alpha; Ll12a; NF cell stimulatory factor chain 1; NFSK; NK cell stimulatory factor chain 1; NKSF1; P35 | |
IL12A | |
Primary | |
Protein A/G |
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