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Invitrogen™ IL-12 p35 Monoclonal Antibody (C1)

Mouse Monoclonal Antibody

$213.50 - $522.50

Specifications

Antigen IL-12 p35
Clone C1
Concentration 1 mg/mL
Content And Storage -20°C
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIMA541614
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Invitrogen™
MA541614
200 μL
Each for $522.50
Only null left
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PIMA543742
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Invitrogen™
MA543742
20 μL
Each for $213.50
Only null left
Add to Cart
 
Description

Description

IL-12 p35 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

Interleukin 12A is a novel signaling cytokine belonging to the Interleukin-6 protein superfamily. Interleukin-12 alpha chain precursor (IL-12A) is a 35-kD subunit of disulfide-linked heterodimer of cytokine IL-12 and has a broad array of biological activities. Reports suggest that IL-12A can act as a growth factor for activated T and NK cells and enhance the lytic activity of NK/lymphokine-activated Killer cells. IL-12A stimulates the production of IFN-gamma by resting PBMC as well as T-cell-independent induction of interferon (IFN)-gamma, and helps in the differentiation of both Th1 and Th2 cells. It is also involved in positive regulation of tyrosine phosphorylation of Stat4 protein. The signaling process of IL-12A in innate immunity requires nitric oxide synthase 2A. Along with EBI3, IL-12A forms a novel heterodimeric cytokine, designated as interleukin-35 (IL-35), that may be specifically produced by T reg cells and is required for maximal suppressive activity.
Specifications

Specifications

IL-12 p35
1 mg/mL
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Unconjugated
Mouse
RUO
PBS with 50% glycerol and 0.05% ProClin 300
P29459
3592
Recombinant protein Interleukin 12A. The antigen corresponds to amino acid range 23-219 of the target protein.
Antibody
C1
-20°C
Monoclonal
Liquid
IgG2b κ
Human
IL12A
CLMF; CLMF p35; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; il 12; IL-12 subunit p35; IL-12, subunit p35; Il12a; IL-12A; IL12p35; IL-12p35; IL35 subunit; ILN; Interleukin; Interleukin 12; interleukin 12 p35 subunit; interleukin 12, p35; interleukin 12a; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); Interleukin12; interleukin-12 alpha chain; interleukin-12 beta p35 subunit; interleukin-12 p35 subunit; interleukin-12 subunit alpha; Ll12a; NF cell stimulatory factor chain 1; NFSK; NK cell stimulatory factor chain 1; NKSF1; P35
IL12A
Primary
Protein A/G
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