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IL-13 Mouse anti-Human, eFluor 450, Clone: 85BRD, eBioscience
Mouse Monoclonal Antibody
Manufacturer: eBioscience 48713642
Description
The 85BRD monoclonal antibody reacts with human interleukin-13 (IL-13). IL-13, also known as NC30, is a 12.5 kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. The biological activities of IL-13 include suppression of macro
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.Specifications
IL-13 | |
Monoclonal | |
5 μL/Test | |
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
P35225 | |
IL13 | |
IgG2b, kappa | |
100 Tests | |
4° C, store in dark, DO NOT FREEZE! | |
Primary | |
3596 |
Flow Cytometry | |
85BRD | |
eFluor™ 450 | |
IL13 | |
Liquid | |
Mouse | |
Affinity Chromatography | |
RUO | |
Antibody | |
Monoclonal | |
Human |
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