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Invitrogen™ IL-16 Polyclonal Antibody
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Catalog No. PIPA520671
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100 μg
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Catalog No. Quantity
PIPA520671 100 μg
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Catalog No. PIPA520671 Supplier Invitrogen™ Supplier No. PA520671
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Rabbit Polyclonal Antibody

A suggested positive control is rat brain tissue lysate. PA5-20671 can be used with blocking peptide PEP-0789.

The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL-16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
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Specifications

Antigen IL-16
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene IL16
Gene Accession No. O54824, Q14005
Gene Alias FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; Il16; IL-16; ILN; Interleukin; interleukin 16; Interleukin16; Interleukin-16; LCF; Lymphocyte chemoattractant factor; M-IL-16; mKIAA4048; neuronal interleukin 16; NIL16; PRIL16; prIL-16; prointerleukin 16; Pro-interleukin-16
Gene Symbols IL16
Host Species Rabbit
Immunogen A 14 amino acid peptide near the amino terminus of human IL-16.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116996, 16170, 3603
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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