Invitrogen™ IL-16 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5145466

Catalog No. FEPA5145466

Description

The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL-16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.

Specifications

• Antigen: IL-16
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IL16
• Gene Alias: FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; Il16; IL-16; ILN; Interleukin; interleukin 16; Interleukin16; Interleukin-16; LCF; Lymphocyte chemoattractant factor; M-IL-16; mKIAA4048; neuronal interleukin 16; NIL16; PRIL16; prIL-16; prointerleukin 16; Pro-interleukin-16
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3603, 374270
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Accession No.: Q14005
• Gene Symbols: IL16
• Immunogen: Recombinant Chicken IL16 protein, Ser1183-Leu1454 (Accession #Q70XC4).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Chicken
• Product Type: Antibody
• Isotype: IgG