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IL-17E Monoclonal Antibody (11K8B1), Rockland™
SDP

Catalog No. 501991354
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100 μg
25 μL
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Catalog No. Quantity
50-199-1354 100 μg
50-199-1355 25 μL
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Catalog No. 50-199-1354 Supplier Rockland Immunochemicals Supplier No. 209301C58
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Description

Mouse Monoclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody is specific for human IL-17E protein. A BLAST analysis was used to suggest cross-reactivity with IL-17E from human sources based on 100% homology with the immunizing sequence. Cross-reactivity with IL-17E from other sources has not been determined.

Interleukin 25 (IL-25) is a member of the IL-17 family and is identified as a proinflammatory cytokine which is produced by Th17 effector cells thus enabling the Th17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis. IL-25 also induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. IL-25 itself is activated through IL-23, IL-5, and TGF-beta.

Specifications

Antigen IL-17E
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 11K8B1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene IL25
Gene Accession No. Q9H293
Gene Alias IL17E; IL-17E; IL25; IL-25; ILN; Interleukin; interleukin 17E; interleukin 25; Interleukin-17E; Interleukin-25; RGD1561632; UNQ3120/PRO10272
Gene Symbols IL25
Host Species Mouse
Immunogen Anti-IL-17E (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17E produced in E.coli followed by hybridoma development.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64806
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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