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IL-17RB Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984849
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50-198-4849 100 μL
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Catalog No. 50-198-4849 Supplier Bioss Supplier No. BS2610R
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Description

Rabbit Polyclonal Antibody

Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.

Specifications

Antigen IL-17RB
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene IL17RB
Gene Accession No. Q9NRM6
Gene Alias CRL4; cytokine receptor CRL4; Cytokine receptor-like 4; ecotropic viral integration site 27; Evi27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B; IL-17B receptor; Il17br; IL-17ER; IL17RB; IL-17RB; IL17RH1; IL-17Rh1; IL-20; interleukin 17 receptor B; interleukin 17 receptor homolog 1; interleukin 17B receptor; Interleukin-17 receptor B; Interleukin-17B receptor; MGC138900; MGC138901; MGC5245; UNQ2501/PRO19612; ZCYTO7
Gene Symbols IL17RB
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human IL-17RB.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55540
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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