Invitrogen™ IL-19 Monoclonal Antibody (152112)

Catalog No.	Quantity
PIMA523778	500 μg

Catalog No. PIMA523778 Supplier Invitrogen™ Supplier No. MA523778

Description

Mouse Monoclonal Antibody

Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.

Specifications

• Antigen: IL-19
• Applications: Flow Cytometry, Neutralization
• Classification: Monoclonal
• Clone: 152112
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: IL19
• Gene Accession No.: Q9UHD0
• Gene Alias: il 19; IL-10C; IL19; IL-19; ILN; Interleukin; interleukin 19; Interleukin19; interleukin-19; MDA1; MDA-1; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein; NG.1; ZMDA1
• Gene Symbols: IL19
• Host Species: Mouse
• Immunogen: E. coli-derived recombinant human IL-19 Leu25-Ala177.
• Purification Method: Protein A/G
• Quantity: 500 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 29949
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2b