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Invitrogen™ IL-19 Recombinant Rabbit Monoclonal Antibody (019)
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Catalog No. PIMA530767
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100 μL
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PIMA530767 100 μL
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Catalog No. PIMA530767 Supplier Invitrogen™ Supplier No. MA530767
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Description

Rabbit Recombinant Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human IL19/Interleukin-19.

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
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Specifications

Antigen IL-19
Applications ELISA
Classification Recombinant Monoclonal
Clone 019
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene IL19
Gene Accession No. Q9UHD0
Gene Alias il 19; IL-10C; IL19; IL-19; ILN; Interleukin; interleukin 19; Interleukin19; interleukin-19; MDA1; MDA-1; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein; NG.1; ZMDA1
Gene Symbols IL19
Host Species Rabbit
Immunogen Recombinant Human IL19/Interleukin-19 Protein (Met1-Ala177).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29949
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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