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Invitrogen™ IL-2 Monoclonal Antibody (B-G5), eBioscience™
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Catalog No. 5017776
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Catalog No. Quantity
50-177-76 100 μg
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Catalog No. 50-177-76 Supplier Invitrogen™ Supplier No. BMS128
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Description

Mouse Monoclonal Antibody

Description: BMS128 (B-G5) detects IL-2 which has a predicted molecular weight of approximately 15 kDa. BMS128 targets IL-2 in ELISA, and WB applications and shows reactivity with Human samples. 50 ng of B-G5 neutralizes 1 unit of IL-2 on CTL.L2, inhibition of proliferation by 50%. Applications Tested: Functional Studies. Purity: >95%.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
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Specifications

Antigen IL-2
Applications Functional Assay
Classification Monoclonal
Clone B-G5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene IL2
Gene Accession No. P60568
Gene Alias aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Gene Symbols IL2
Host Species Mouse
Immunogen Rec. Human IL-2.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3558
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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