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Invitrogen™ IL-2 Monoclonal Antibody (JES6-5H4), eBioscience™

Rat Monoclonal Antibody

Supplier:  Invitrogen™ BMS180

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Catalog No. 50-178-49


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Description

Description

Description: BMS180 (JES6-5H4) is raised against recombinant full length IL-2 of mouse origin and recommended for detection of recombinant and native IL-2 of mouse origin by IP,ELISA, FC, WB. The antibody was purified from tissue culture supernatant by protein G column chromatography. Applications Tested: ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blotting.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

IL-2
Monoclonal
0.5 mg/mL
PBS with no preservative; pH 7.4
P04351
IL2
Rec. Mouse IL-2.
100 μg
Primary
Mouse
Antibody
IgG2b
ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
JES6-5H4
Unconjugated
IL2
aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Rat
Affinity chromatography
RUO
16183
4°C
Liquid
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