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  6. Invitrogen™ IL-2 Monoclonal Antibody (JES6-5H4), PE-eFluor™ 610, eBioscience™, Invitrogen™ 

Invitrogen™ IL-2 Monoclonal Antibody (JES6-5H4), PE-eFluor™ 610, eBioscience™, Invitrogen™
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Catalog No. 61702182
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100 μg
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Catalog No. Quantity
61-702-182 100 μg
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Catalog No. 61-702-182 Supplier Invitrogen™ Supplier No. 61702182
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Description

Rat Monoclonal Antibody

The JES6-5H4 antibody reacts with mouse interleukin-2 (IL-2), a 17 kDa T cell growth factor and a major immunoregulatory cytokine.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
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Specifications

Antigen IL-2
Applications Flow Cytometry
Classification Monoclonal
Clone JES6-5H4
Concentration 0.2 mg/mL
Conjugate PE-eFluor 610
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene IL2
Gene Accession No. P04351
Gene Alias aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Gene Symbols IL2
Host Species Rat
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16183
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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Safety and Handling

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