Invitrogen™ IL-2 Polyclonal Antibody

Catalog No.	Quantity
PIPA585127	100 μL

Catalog No. PIPA585127 Supplier Invitrogen™ Supplier No. PA585127

Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Rhesus Monkey (97%). Positive Control: Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

Specifications

• Antigen: IL-2
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.82 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene: IL2
• Gene Accession No.: P60568
• Gene Alias: aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
• Gene Symbols: IL2
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the center region of human IL2. The exact sequence is proprietary.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3558
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Frequently Asked Questions (FAQs)

Can you provide the exact immunogen sequence for IL-2 Polyclonal Antibody (Cat. No. PA5-85127)?

The exact immunogen sequence for IL-2 Polyclonal Antibody (Cat. No. PA5-85127) is proprietary. However, we can divulge that the immunogen is a recombinant protein encompassing a sequence within the center region of human IL-2.