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IL-2 Rat anti-Human, Rhesus, Cynomolgus, Baboon, Brilliant Violet 750, Clone: MQ1-17H12, BD

Catalog No. BDB566361 Shop All BD Biosciences Products
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BDB566361 50 μg
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Catalog No. BDB566361 Supplier BD Biosciences Supplier No. 566361
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Rat Monoclonal Antibody

The MQ1-17H12 monoclonal antibody specifically binds to the multifunctional cytokine, human Interleukin-2 (IL-2). IL-2 is produced by activated T cells and has multiple functions that can affect the growth, proliferation, differentiation and survival of many different target cell types including T cells, B cells, NK cells, monocytes and macrophages. The immunogen used to generate the MQ1-17H12 hybridoma was purified recombinant human IL-2 protein. The MQ1-17H12 antibody reportedly neutralizes the biological activity of human IL-2.

The antibody was conjugated to BD Horizon BV750 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 750nm. BD Horizon Brilliant BV750 can be excited by the violet laser (405 nm) and detected with a 750/30 nm filter with a 740 nm long pass. Due to spectral differences between labeled cells and beads, using BD™ CompBeads can result in incorrect spillover values when used with BD Horizon BV750 reagents. Therefore, the use of BD CompBeads or BD CompBeads Plus to determine spillover values for these reagents is not recommended. BV750
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-2
Classification Monoclonal
Clone MQ1-17H12
Concentration 0.2mg/mL
Conjugate Brilliant Violet 750
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias IL2, Interleukin-2, T-cell growth factor, TCGF
Host Species Rat
Immunogen Human IL-2 Recombinant Protein
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Baboon, Cynomolgus, Human, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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