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IL-2 Rat anti-Mouse, Clone: JES6-5H4, eBioscience™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

$85.75 - $249.00

Specifications

Antigen IL-2
Clone JES6-5H4
Target Species Mouse
Conjugate Unconjugated
Isotype IgG2b, kappa
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-135-96 Non-distribution product as customer accommodation.
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Invitrogen
14702181
50 μg
Each for $85.75
Add to cart
 
50-135-97 Non-distribution product as customer accommodation.
View Documents
Invitrogen
14702185
500 μg
Each for $249.00
Add to cart
 
Description

Description

Description: The JES6-5H4 antibody reacts with mouse interleukin-2 (IL-2), a 17 kDa T cell growth factor and a major immunoregulatory cytokine. Applications Reported: The purified JES6-5H4 has been reported for use in blocking of fluorochrome conjugated JES6-5H4 in intracellular flow cytometry experiments to serve as specificity control. JES6-5H4 is reported for detection of mouse IL-2 by ELISA, immunoprecipitation, and for neutralizing IL-2 binding and biological activity (use Functional Grade purified). Applications Tested: The JES6-5H4 antibody has been tested by sandwich ELISA for detection of mouse IL-2 in combination with JES6-1A12 and can be used between 0.5-2 µg/mL. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
Specifications

Specifications

IL-2
Mouse
IgG2b, kappa
Monoclonal
Liquid
Antibody
4° C
JES6-5H4
Unconjugated
Flow Cytometry, Immunoprecipitation
Primary
Monoclonal
PBS with 0.09% sodium azide; pH 7.2
RUO
SDS

For Research Use Only.

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