IL-2 Rat anti-Mouse, PE, Clone: JES6-5H4, BD

Rat Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB561061	BD Biosciences 561061	25 μg
BDB554428	BD Biosciences 554428	0.1 mg

Description

The JES6-5H4 monoclonal antibody specifically binds to mouse interleukin-2 (IL-2). IL-2 is a multifunctional cytokine that plays pivotal roles in immunity and tolerance. It is produced by activated T cells. IL-2 effects the activation, growth, proliferation and/or differentiation of various cell types including T and B lymphocytes and their precursors, LAK cells, NK cells, and monocytes/macrophages. IL-2 mediates its biological activities by binding to IL-2 receptor compleses. The intermediate affinity IL-2R is comprised of IL-2R β (CD122) and common gamma chain ( γc; CD132) subunits whereas the high-affinity IL-2R is comprised of IL-2R α (CD25), IL-2R β and γc subunits. The JES6-5H4 monoclonal antibody binds to IL-2 and neutralizes its biological activity.

Specifications

• Antigen: IL-2
• Concentration: 0.2mg/mL
• Classification: Monoclonal
• Host Species: Rat
• Target Species: Mouse
• Isotype: IgG2b
• Purification Method: Affinity Purified

• Clone: JES6-5H4
• Applications: Flow Cytometry
• Conjugate: PE
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.