IL-27RA Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS2711R

Catalog No. 50-198-4918

Description

Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.

Specifications

• Antigen: IL-27RA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Il27ra
• Gene Alias: class I cytokine receptor; CRL1; CRL1IL-27R; cytokine receptor family, class 1 (WSXWS), member 1; Cytokine receptor WSX-1; Cytokine receptor-like 1; IL-27 receptor subunit alpha; IL27R; IL-27R; IL-27R subunit alpha; IL27RA; IL-27RA; IL-27R-alpha; interleukin 27 receptor subunit alpha; interleukin 27 receptor, alpha; Interleukin-27 receptor subunit alpha; T cell cytokine receptor; T cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1; TCCR; T-cell cytokine receptor type 1; Type I T-cell cytokine receptor; UNQ296/PRO336; WSX1; WSX-1; ZcytoR1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 9466
• Content And Storage: -20°C
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q6UWB1
• Gene Symbols: Il27ra
• Immunogen: KLH conjugated synthetic peptide derived from human IL-27RA.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG