Invitrogen™ IL-28A/IL-28B Monoclonal Antibody (244716)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA523902

Catalog No. PIMA523902

Description

In sandwich ELISAs, 100% cross-reactivity with recombinant mouse IL-28A/IFN-lambda 2 and no cross-reactivity with recombinant human (rh) IL-28A or rhIL-29 is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

IL28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

Specifications

• Antigen: IL-28A/IL-28B
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q4VK74, Q8CGK6
• Gene Symbols: Ifnl2, Ifnl3
• Immunogen: E. coli-derived recombinant mouse IL-28B/IFN-lambda3 Asp20-Val193.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Neutralization
• Clone: 244716
• Conjugate: Unconjugated
• Gene: Ifnl3
• Gene Alias: Cytokine Zcyto20; cytokine Zcyto22; EG330496; IFL-1; IFN lambda2; Ifnl2; Ifnl3; IFN-lambda2; IFN-lambda-2; IFN-lambda-3; IFN-lambda-4; IL 28; IL 28 A; Il28; Il28a; IL-28A; Il28b; IL-28B; IL28C; IL-28C; ILN; INF-alpha; INF-lambda; interferon alpha; interferon lambda 2; interferon lambda 3; Interferon lambda2; interferon lambda-2; Interferon lambda-3; interferon, lambda 2; interferon, lambda 3; interferon, lambda 4; interferon-lambda 2; interferon-lambda2; Interleukin; interleukin 28; interleukin 28A; interleukin 28A (interferon, lambda 2); interleukin 28B; interleukin-28A; Interleukin-28B; interleukin-28C; ZCYTO20; ZCYTO22
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 330496, 338374
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized