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Invitrogen™ IL-28A/IL-28B Monoclonal Antibody (244716)
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Catalog No. PIMA523902
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100 μg
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Catalog No. Quantity
PIMA523902 100 μg
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Catalog No. PIMA523902 Supplier Invitrogen™ Supplier No. MA523902
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Description

Rat Monoclonal Antibody

In sandwich ELISAs, 100% cross-reactivity with recombinant mouse IL-28A/IFN-lambda 2 and no cross-reactivity with recombinant human (rh) IL-28A or rhIL-29 is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

IL28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
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Specifications

Antigen IL-28A/IL-28B
Applications ELISA, Neutralization
Classification Monoclonal
Clone 244716
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Ifnl3
Gene Accession No. Q4VK74, Q8CGK6
Gene Alias Cytokine Zcyto20; cytokine Zcyto22; EG330496; IFL-1; IFN lambda2; Ifnl2; Ifnl3; IFN-lambda2; IFN-lambda-2; IFN-lambda-3; IFN-lambda-4; IL 28; IL 28 A; Il28; Il28a; IL-28A; Il28b; IL-28B; IL28C; IL-28C; ILN; INF-alpha; INF-lambda; interferon alpha; interferon lambda 2; interferon lambda 3; Interferon lambda2; interferon lambda-2; Interferon lambda-3; interferon, lambda 2; interferon, lambda 3; interferon, lambda 4; interferon-lambda 2; interferon-lambda2; Interleukin; interleukin 28; interleukin 28A; interleukin 28A (interferon, lambda 2); interleukin 28B; interleukin-28A; Interleukin-28B; interleukin-28C; ZCYTO20; ZCYTO22
Gene Symbols Ifnl2, Ifnl3
Host Species Rat
Immunogen E. coli-derived recombinant mouse IL-28B/IFN-lambda3 Asp20-Val193.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 330496, 338374
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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