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IL-33R (ST2) Rat anti-Mouse, PE, Clone: U29-93, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 566311

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Catalog No. BDB566311


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Description

Description

The U29-93 monoclonal antibody specifically binds to the mouse Interleukin-33 Receptor (IL-33 Receptor, or IL-33R) which is also known as ST2. The IL-33R exists in either a type I transmembrane or soluble glycoprotein form. These IL-33R forms are encoded by the Il1rl1 (Interleukin-1 receptor-like 1) gene which belongs to the IL-1 Receptor family within the Ig superfamily. The IL-33R is expressed by subsets of T cells, including Th2-like cells and some regulatory T cells, as well as some innate lymphocytes, eosinophils, basophils, and mast cells. The IL-33R (also known as the IL-33R alpha subunit, or binds IL-33 and complexes with the IL-1R Accessory Protein (IL1RAP) to form a functional signaling receptor complex that can induce the production of T helper type 2 (Th2) cytokines. The soluble IL-33R may function as a decoy receptor which can block the binding of IL-33 to the transmembrane IL-33R. The IL-33R plays roles in inflammation, immunity, and allergy.

R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.
Specifications

Specifications

IL-33R (ST2)
0.2mg/mL
Aqueous buffered solution containing ≤0.09% sodium azide.
Il1rl1, ST2, ST2L, IL-33R alpha, IL-33Rα, IL33RA, Ly84, DER4, Fit-1
Mouse IL-33R Recombinant Protein
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
RUO
Primary
Murine
U29-93
PE
Affinity Purified
Rat
Rat IgG2a, κ
100μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
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