Invitrogen™ IL-34 Monoclonal Antibody (1D12)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA517098

Catalog No. PIMA517098

Description

MA5-17098 targets IL34 in indirect ELISA, FACS, ICC, IF, and WB applications and shows reactivity with Human samples. The MA5-17098 immunogen is purified recombinant fragment of human IL34 expressed in E. Coli. MA5-17098 detects IL34 which has a predicted molecular weight of approximately 27.5kDa.

IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.

Specifications

• Antigen: IL-34
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: Q6ZMJ4
• Gene Symbols: Il34
• Immunogen: Purified recombinant fragment of human IL34 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 146433
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 1D12
• Conjugate: Unconjugated
• Gene: Il34
• Gene Alias: 2010004A03Rik; AI593503; C16orf77; IL34; IL-34; ILN; Interleukin; interleukin 34; Interleukin34; interleukin-34
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1