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Invitrogen™ IL-35 Recombinant Rabbit Monoclonal Antibody (6H15L18)

Catalog No. PI701101
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100 μg
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PI701101 100 μg
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Catalog No. PI701101 Supplier Invitrogen™ Supplier No. 701101
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Description

Rabbit Recombinant Monoclonal Antibody

Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

IL-35, or Interleukin 35 is a cytokine belonging to the IL12 family, that is produced by regulatory T cells. It is a dimeric protein composed of IL-12-alpha and IL-27-beta chains. Members of this class of cytokines are important in influencing T helper cell differentiation and supressing inflammatory response. IL-35 is known to induce proliferation of regulatory T cells, and reduce the activity of helper Th17 cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-35
Applications Western Blot
Classification Recombinant Monoclonal
Clone 6H15L18
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene IL12A
Gene Accession No. P29459
Gene Alias CLMF; CLMF p35; cytokine receptor; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; EBI3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; epstein-Barr virus-induced gene 3 protein; IL-12 subunit p35; IL-12, subunit p35; IL12A; IL-12A; IL12p35; IL27 subunit; IL-27 subunit beta; IL27B; IL-27B; il35; IL35 subunit; ILN; Interleukin; interleukin 12, p35; interleukin 12A; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin-12 alpha chain; interleukin-12 subunit alpha; Interleukin-27 subunit beta; Interleukin-35; NF cell stimulatory factor chain 1; NFSK; NK cell stimulatory factor chain 1; NKSF1; P35
Gene Symbols IL12A
Host Species Rabbit
Immunogen Recombinant protein corresponding to amino acids 57-186 of human interleukin 35.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3592
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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