Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
IL-4 Monoclonal Antibody (11B11), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
$3270.00 - $3545.00
Specifications
| Antigen | IL-4 |
|---|---|
| Clone | 11B11 |
| Concentration | 1 mg/mL |
| Classification | Monoclonal |
| Conjugate | Functional Grade |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
16-704-138
|
LIFE TECHNOLOGIES
16704138 |
5 mg |
Each for $3,270.00
|
|
|||||
|
16-704-195
|
LIFE TECHNOLOGIES
16704195 |
10 mg |
Each for $3,545.00
|
|
|||||
Description
The 11B11 antibody reacts with mouse interleukin-4 (IL-4), a 14 kD cytokine. The 11B11 antibody is a neutralizing antibody. Mouse IL-4, also known as BCDF, BCGF-1 and BSF-1, is secreted by activated Th2 and natural killer T cells, and to a lesser extent by Th1 and mast cells. IL-4 is species-specific and promotes proliferation and differentiation of B cells. IL-4, in conjunction with other signals such as CD40, induces Ig isotype switching of B cells and the upregulation of surface MHC class II and CD23.
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.Specifications
| IL-4 | |
| 1 mg/mL | |
| Functional Grade | |
| Rat | |
| Mouse | |
| P07750 | |
| IgG1 κ | |
| Affinity chromatography | |
| Antibody |
| 11B11 | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with no preservative; pH 7.2 | |
| 16189 | |
| Primary | |
| 4°C | |
| Il4 |
Spot an opportunity for improvement?Share a Content Correction
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title