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Invitrogen™ IL-4 Monoclonal Antibody (3010)
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Catalog No. PIMA523692
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500 μg
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Catalog No. Quantity
PIMA523692 500 μg
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Catalog No. PIMA523692 Supplier Invitrogen™ Supplier No. MA523692
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Description

Mouse Monoclonal Antibody

In sandwich ELISAs, no cross-reactivity or interference was observed with recombinant human (rh) IL-1 alpha, rhIL-1 beta, rhIL-2, rhIL-3, rhIL-6, rhIL-7, rhIL-8, rhG-CSF, rhGM-CSF, rhTNF-alpha, rhTNF- beta, rhLIF, rhTGF- beta 1, recombinant mouse (rm) IL-1 beta, rmIL-6, rmIL-7, rmGM-CSF, bovine FGF acidic, bovine FGF basic, porcine PDGF, human TGF- beta 1, porcine TGF- beta 1.2, and porcine TGF- beta 2. Reconstitute at 0.5 mg/mL in sterile PBS.

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-4
Applications ELISA, Western Blot
Classification Monoclonal
Clone 3010
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Il4
Gene Accession No. P05112
Gene Alias B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
Gene Symbols Il4
Host Species Mouse
Immunogen E. coli-derived recombinant human IL-4 His25-Ser153.
Purification Method Protein A/G
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3565
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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