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Invitrogen™ IL-5 Chimeric Recombinant Rabbit Monoclonal Antibody (2E3)
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Catalog No. PIMA548177
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200 μg
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PIMA548177 200 μg
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Catalog No. PIMA548177 Supplier Invitrogen™ Supplier No. MA548177
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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: This antibody is specific for human rIL-5, and does not cross-react with human rIL-1alpha, rIL-lBeta, rIL-4, rIL-8, rM-CSF, or rTGF-alpha.

IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
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Specifications

Antigen IL-5 Chimeric
Applications ELISA, Flow Cytometry, Neutralization
Classification Recombinant Monoclonal
Clone 2E3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene Il5
Gene Accession No. P05113
Gene Alias B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF
Gene Symbols Il5
Host Species Rabbit
Immunogen This antibody was raised by immunising CAF1 mice with human recombinant IL-5.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3567
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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