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Invitrogen™ IL-5 Monoclonal Antibody (TRFK5), eBioscience™
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Catalog No. 5017848
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Catalog No. Quantity
50-178-48 100 μg
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Catalog No. 50-178-48 Supplier Invitrogen™ Supplier No. BMS179
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Description

Rat Monoclonal Antibody

The TRFK5 antibody reacts with mouse interleukin-5 (IL-5) and cross-reacts with human IL-5. The TRFK5 antibody has been reported to cross react with IL-5 from rhesus monkey. Applications Tested: ELISA, Flow Cytometry (Intracellular Staining).

IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
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Specifications

Antigen IL-5
Applications ELISA, Flow Cytometry
Classification Monoclonal
Clone TRFK5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with no preservative; pH 8.0
Gene Il5
Gene Accession No. P04401
Gene Alias B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF
Gene Symbols Il5
Host Species Rat
Immunogen Rec. Mouse IL-5.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16191
Target Species Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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