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Invitrogen™ IL-6 Monoclonal Antibody (B-E8), FITC, eBioscience™
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Catalog No. 5017780
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100 Tests
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Catalog No. Quantity
50-177-80 100 Tests
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Catalog No. 50-177-80 Supplier Invitrogen™ Supplier No. BMS130FI
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Description

Mouse Monoclonal Antibody

Description: BMS130FI (B-E8) recognizes natural and recombinant forms of human Interleukin-6 with an affinity of 0.5 nM. Inhibits IL-6 binding to its receptors and blocks Interleukin-6 induced proliferation on B9 cells. Applications Tested: Flow Cytometry (Intracellular Staining). Purity: >95%. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.

IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.
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Specifications

Antigen IL-6
Applications Flow Cytometry, Functional Assay
Classification Monoclonal
Clone B-E8
Concentration 10 μL/Test
Conjugate FITC
Formulation TBS with 1% BSA and 0.02% sodium azide; pH 7.2-7.4
Gene Il6
Gene Accession No. P05231
Gene Alias B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
Gene Symbols Il6
Host Species Mouse
Purification Method Affinity chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3569
Target Species Human
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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