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Invitrogen™ IL-6 Receptor Recombinant Rabbit Monoclonal Antibody (033), PE
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Catalog No. PIMA546808
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100 Tests
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Catalog No. Quantity
PIMA546808 100 Tests
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Catalog No. PIMA546808 Supplier Invitrogen™ Supplier No. MA546808
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Description

Rabbit Recombinant Monoclonal Antibody

Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-6 Receptor (CD126) (Ile44-Glu357) and conjugated with PE under optimum conditions, the unreacted PE was removed. Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
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Specifications

Antigen IL-6 Receptor
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone 033
Concentration 100 μg/mL
Conjugate PE
Formulation PBS with 0.5% BSA and 0.09% sodium azide
Gene Il6ra
Gene Accession No. P22272
Gene Alias CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991
Gene Symbols Il6ra
Host Species Rabbit
Immunogen Recombinant protein encoding Mouse IL-6 Receptor (Ile44-Glu357).
Purification Method Protein A
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16194
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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