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Invitrogen™ Human IL-6R (soluble) Recombinant Protein
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Quantity:
100 μg
Description
This product contains purified recombinant human IL-6 Soluble Receptor protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Specifications
Specifications
Accession Number | P08887 |
Concentration | 0.55 mg/mL |
For Use With (Application) | Control, Western Blot |
Formulation | 20 mM tris HCl with 50% glycerol and no preservative; pH 8 |
Gene ID (Entrez) | 3570 |
Name | Human IL-6 R (soluble) |
Quantity | 100 μg |
Source | E. Coli |
Immunogen | N/A |
Regulatory Status | RUO |
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Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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