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IL-6R Beta/CD130/gp130 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983305
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50-198-3305 100 μL
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Catalog No. 50-198-3305 Supplier Bioss Supplier No. BS1459R
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Description

Rabbit Polyclonal Antibody

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Specifications

Antigen IL-6R Beta/CD130/gp130
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene IL6ST
Gene Accession No. P40189
Gene Alias 5133400A03Rik; AA389424; Ac1055; BB405851; CD130; CD130 antigen; CDw130; D13Ertd699e; EGK_16499; gp130; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; gp130, oncostatin M receptor; GP130-RAPS; IL-6; IL-6 receptor subunit beta; IL-6R subunit beta; Il-6rb; IL-6R-beta; IL6R-beta; IL6ST; interleukin 6 signal transducer; interleukin 6 signal transducer (gp130, oncostatin M receptor); interleukin 6 signal transducer receptor; interleukin receptor beta chain; Interleukin-6 receptor subunit beta; Interleukin-6 signal transducer; Membrane glycoprotein 130; membrane glycoprotein gp130; Oncostatin-M receptor subunit alpha
Gene Symbols IL6ST
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from mouse IL6R beta.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3572
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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