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Invitrogen™ IL10RA Monoclonal Antibody (8A2A5)
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Catalog No. FERMA548508
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100 μg
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Catalog No. Quantity
FERMA548508 100 μg
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Catalog No. FERMA548508 Supplier Invitrogen™ Supplier No. MA548508
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Description

Mouse Monoclonal Antibody

IL10RA Monoclonal Antibody for Western Blot, ICC/IF, Flow, ELISA

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL10RA
Applications ELISA, Flow Cytometry, Western Blot, Immunocytochemistry, Western Blot
Classification Monoclonal
Clone 8A2A5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Il10ra
Gene Accession No. Q13651
Gene Alias AW553859; CD210; CD210a; CDw210; CDW210A; CDW210B; CRF2-4; CRFB4; D21S58; D21S66; HIL-10R; I10R; I10R1; il-10 receptor; il-10 receptor antagonist; IL-10 receptor subunit alpha; IL10R; IL-10R alpha; IL-10R subunit 1; IL-10R subunit alpha; IL-10R1; IL-10R2; Il10ra; IL-10RA; interleukin 10 receptor subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; interleukin-10 receptor subunit 1; Interleukin-10 receptor subunit alpha; mIL-10R
Gene Symbols Il10ra
Host Species Mouse
Immunogen Purified recombinant fragment of human CD210 (AA: extra 22-235)) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3587
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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