IL10RA Monoclonal Antibody (OTI1C7), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-6860	100 μL

Catalog No. 50-167-6860 Supplier OriGene Supplier No. TA506931

Description

Mouse Monoclonal Antibody

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Specifications

• Antigen: IL10RA
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI1C7
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: IL10RA
• Gene Accession No.: Q13651
• Gene Alias: CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R
• Gene Symbols: IL10RA
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human IL10RA produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3587
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1