IL10RA Monoclonal Antibody (OTI1G10), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA506955

Catalog No. 50-167-6877

Description

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Specifications

• Antigen: IL10RA
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q13651
• Gene Symbols: IL10RA
• Immunogen: Full length human recombit protein of human IL10RA produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI1G10
• Conjugate: Unconjugated
• Gene: IL10RA
• Gene Alias: CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3587
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid