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Invitrogen™ IL10RA Polyclonal Antibody
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Catalog No. PIPA527772
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100 μL
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PIPA527772 100 μL
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Catalog No. PIPA527772 Supplier Invitrogen™ Supplier No. PA527772
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2, HCT116. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL10RA
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.68 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Il10ra
Gene Accession No. Q13651, Q61727
Gene Alias AW553859; CD210; CD210a; CDw210; CDW210A; CDW210B; CRF2-4; CRFB4; D21S58; D21S66; HIL-10R; I10R; I10R1; il-10 receptor; il-10 receptor antagonist; IL-10 receptor subunit alpha; IL10R; IL-10R alpha; IL-10R subunit 1; IL-10R subunit alpha; IL-10R1; IL-10R2; Il10ra; IL-10RA; interleukin 10 receptor subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; interleukin-10 receptor subunit 1; Interleukin-10 receptor subunit alpha; mIL-10R
Gene Symbols Il10ra
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Intracellular domain of human IL10 Receptor alpha. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16154, 3587
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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