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Invitrogen™ IL12RB2 Polyclonal Antibody
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Catalog No. PA550685
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100 μL
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PA550685 100 μL
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Catalog No. PA550685 Supplier Invitrogen™ Supplier No. PA550685
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total IL12RB2 protein.

The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL12RB2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene IL12RB2
Gene Accession No. Q99665
Gene Alias A930027I18Rik; Ifnm; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; Il12rb2; IL-12RB2; IL-12R-beta-2; interferon response to microorganisms; interleukin 12 receptor subunit beta 2; interleukin 12 receptor, beta 2; interleukin-12 receptor beta-2 chain; interleukin-12 receptor subunit beta-2; RP11-102M16.1
Gene Symbols IL12RB2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region derived from internal residues of human interleukin 12 receptor, beta 2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3595
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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