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Invitrogen™ IL12RB2 Polyclonal Antibody
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Catalog No. PIPA5141067
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100 μL
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PIPA5141067 100 μL
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Catalog No. PIPA5141067 Supplier Invitrogen™ Supplier No. PA5141067
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Description

Rabbit Polyclonal Antibody

IL12RB2 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL12RB2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene IL12RB2
Gene Accession No. Q99665
Gene Alias A930027I18Rik; Ifnm; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; Il12rb2; IL-12RB2; IL-12R-beta-2; interferon response to microorganisms; interleukin 12 receptor subunit beta 2; interleukin 12 receptor, beta 2; interleukin-12 receptor beta-2 chain; interleukin-12 receptor subunit beta-2; RP11-102M16.1
Gene Symbols IL12RB2
Host Species Rabbit
Immunogen Synthetic peptide within human IL-12RB2 aa 751-800.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3595
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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