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IL17A Mouse anti-Human, Clone: 4K5F6, Abnova™

Catalog No. 89934362 Shop All Abnova Corporation Products
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89-934-362 50 μg
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Catalog No. 89-934-362 Supplier Abnova Corporation Supplier No. MAB12727
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Description

Mouse monoclonal antibody raised against human IL17A.

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq]

Specifications

Antigen IL17A
Applications Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot
Classification Monoclonal
Clone 4K5F6
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against human IL17A.
Dilution Flow Cytometry Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL) Western Blot (0.2-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.05% BSA, 0.05% sodium azide).
Gene Alias CTLA8/IL-17/IL-17A/IL17
Gene Symbols IL17A
Host Species Mouse
Immunogen A peptide corresponding to amino acids 1-75 of human IL17A.
Purification Method Protein G purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3605
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG2b κ
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