IL17RB Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-3029	Proteintech Group Inc 206731AP150UL	150 μL

Description

The antibody is specific to IL17RB.

Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.

Specifications

• Antigen: IL17RB
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q9JIP3, Q9NRM6
• Gene ID (Entrez): 50905, 55540
• Immunogen: Peptide
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: IL17RB

• Concentration: 0.43 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CRL4, Cytokine receptor like 4, EVI27, IL 17 receptor B, IL 17 receptor homolog 1, IL 17B receptor, IL 17RB, IL 17Rh1, IL17BR, IL17RB, IL17RH1, interleukin 17 receptor B, Interleukin 17B receptor
• Gene Symbols: Il17rb
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody