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Invitrogen™ IL17RC Monoclonal Antibody (02), Invitrogen™

Catalog No. PIMA543494
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PIMA543494 50 μL
PIMA543029 100 μL
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Catalog No. PIMA543494 Supplier Invitrogen™ Supplier No. MA543494
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Description

Mouse Monoclonal Antibody

Specificity: Human IL17RC

This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL17RC
Applications ELISA
Classification Monoclonal
Clone 02
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene IL17RC
Gene Accession No. Q8NAC3
Gene Alias 1110025H02Rik; CANDF9; Gm19850; IL-17 receptor C; IL17F receptor; IL17RC; IL-17RC; IL17-RC; IL17Rhom; Il17rl; IL-17RL; IL17-RL; interleukin 17 receptor C; interleukin-17 receptor C; Interleukin-17 receptor homolog; interleukin-17 receptor-like protein; UNQ6118/PRO20040/PRO38901; ZcytoR14
Gene Symbols IL17RC
Host Species Mouse
Immunogen Recombinant Human IL17RC protein.
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84818
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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