IL17RC Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-0375	Proteintech Group Inc 156481AP150UL	150 μL

Description

This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predomitly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.

Specifications

• Antigen: IL17RC
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q8K4C2, Q8NAC3
• Gene ID (Entrez): 171095, 84818
• Immunogen: IL17RC Fusion Protein Ag8190
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: IL17RC

• Concentration: 0.15 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: IL 17 receptor C, IL 17RC, IL 17RL, IL17 RL, IL17RC, IL17Rhom, IL17RL, interleukin 17 receptor C, ZcytoR14
• Gene Symbols: Il17rc
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody