Invitrogen™ IL17RE Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534499

Catalog No. PIPA534499

Description

A suggested positive control is human ovary tissue lysate. PA5-34499 can be used with blocking peptide PEP-1542.

The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.

Specifications

• Antigen: IL17RE
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IL17RE
• Gene Alias: AA589509; IL-17 receptor E; IL17RE; IL-17RE; Il25r; interleukin 17 receptor E; interleukin-17 receptor E; UNQ3056/PRO9877
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 132014, 362417, 57890
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q6AZ51, Q8BH06, Q8NFR9
• Gene Symbols: IL17RE
• Immunogen: A 16 amino acid peptide near the center of human IL-17RE.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG