Invitrogen™ IL17RE Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589747

Catalog No. PIPA589747

Description

Immunogen sequence: AGIGFRHLPH WNTRCPLASH TDDSFTGSSA YIPCRTWWAL FSTKPWCVRV WHCSRCLCQH LLSGGSGLQR GLFHLLVQKS KKSSTFKFYR RHKMPAPAQR KLLPRRHLSE KSHHISIPSP DISHKGLRSK RTQPSDPETW ESLPRLDSQR HGGPEFSFDL LPEARAIRVT ISSGPEVSVR LCHQWALECE ELSSPYDVQK IVSGGHTVEL PYEFLLPCLC IEASYLQEDT VRRKKCP; Positive Samples: HT-29, A-549, A-431, Mouse kidney, Mouse thymus; Cellular Location: Cell membrane, Cytoplasm, Single-pass type I membrane protein.

The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.

Specifications

• Antigen: IL17RE
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IL17RE
• Gene Alias: AA589509; IL-17 receptor E; IL17RE; IL-17RE; Il25r; interleukin 17 receptor E; interleukin-17 receptor E; UNQ3056/PRO9877
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 132014, 57890
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.98 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q8BH06, Q8NFR9
• Gene Symbols: IL17RE
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-260 of human IL17RE (NP_7056131).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG