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Description
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq]
Specifications
Specifications
| Antigen | IL1A |
| Applications | ELISA, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against human IL1A. |
| Dilution | ELISA Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:400) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide). |
| Gene Alias | IL-1A/IL1/IL1-ALPHA/IL1F1 |
| Gene Symbols | IL1A |
| Host Species | Mouse |
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