Invitrogen™ IL1R2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102514

Catalog No. PIPA5102514

Description

Antibody detects endogenous levels of total IL1R2.

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.

Specifications

• Antigen: IL1R2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Il1r2
• Gene Alias: antigen CDw121b; CD121 antigen-like family member B; CD121b; CDw121b; IL-1 receptor beta chain; IL-1 type II receptor; Il1r2; Il-1r2; IL-1R-2; Il1r-2; IL1R2c; IL1RB; IL-1R-beta; IL-1RT2; IL-1RT-2; ILR2; interleukin 1 receptor type 2; interleukin 1 receptor type II variant 3; interleukin 1 receptor, type II; interleukin-1 receptor beta; Interleukin-1 receptor type 2; Interleukin-1 receptor type 2, membrane form; Interleukin-1 receptor type 2, soluble form; Interleukin-1 receptor type II; mIL-1R2; sIL-1R2; type II interleukin-1 receptor, beta
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16178, 7850
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P27930, P27931
• Gene Symbols: Il1r2
• Immunogen: A synthesized peptide derived from human IL1R2(Accession P27930), corresponding to amino acid residues L354-K398.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov