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Invitrogen™ IL1RA Monoclonal Antibody (10309)
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Catalog No. PIMA523802
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PIMA523802 1 mg
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Catalog No. PIMA523802 Supplier Invitrogen™ Supplier No. MA523802
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Description

Mouse Monoclonal Antibody

In ELISAs, this antibody shows less than 0.2% cross-reactivity with recombinant mouse (rm) IL-1ra and no cross-reactivity with rhIL-1 alpha, rpIL-1 alpha, rmIL-1 alpha, rrIL-1 alpha, rhIL-1 beta, rpIL-1 beta, rmIL-1 beta, rrIL-1 beta, rhIL-1 RI, or rhIL-1 RII. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL1RA
Applications ELISA, Neutralization
Classification Monoclonal
Clone 10309
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene IL1RN
Gene Accession No. P18510
Gene Alias Anakinra; CD121A; cytokine; D2S1473; DIRA; F630041P17Rik; ICIL-1RA; IL 1 receptor antagonist; IL1 inhibitor; il1 receptor; il-1 receptor; IL1 receptor antagonist; IL1F3; IL1R; il-1r; IL1RA; IL-1RA; IL1-RA; IL-1ra3; IL-1R-alpha; IL1RN; IL-1RN; IL1RN (IL1F3); interleukin 1 receptor antagonist; interleukin-1 receptor; interleukin-1 receptor antagonist; interleukin-1 receptor antagonist protein; interleukin-1 receptor antagonist secretory form; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); IRAP; IRAP1; MGC10430; MVCD4; P80; type II interleukin-1 receptor antagonist
Gene Symbols IL1RN
Host Species Mouse
Immunogen E. coli-derived recombinant human IL-1ra/IL-1F3 Arg26-Glu177.
Purification Method Protein A/G
Quantity 1 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3557
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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