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Invitrogen™ IL1RA Monoclonal Antibody (35730 (49/20))
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Catalog No. PIMA182844
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100 μg
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PIMA182844 100 μg
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Catalog No. PIMA182844 Supplier Invitrogen™ Supplier No. MA182844
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Description

Mouse Monoclonal Antibody

This antibody does not react with rmIL-1 RI or rhIL-1 RII in either Western blot or ELISA applications. Mouse anti human CD121a, clone 35730, recognizes interleukin-1 receptor type 1 (IL1R1). IL1RA/CD121a is widely expressed in a number of cell types including T cells and fibroblasts (Sims et al.)and is involved in the activation of NF-kappa-B (Slack et al.).

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL1RA
Applications ELISA, Western Blot
Classification Monoclonal
Clone 35730 (49/20)
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with <5% trehalose and 0.09% sodium azide; pH 7.2
Gene IL1RN
Gene Accession No. P18510
Gene Alias Anakinra; CD121A; cytokine; D2S1473; DIRA; F630041P17Rik; ICIL-1RA; IL 1 receptor antagonist; IL1 inhibitor; il1 receptor; il-1 receptor; IL1 receptor antagonist; IL1F3; IL1R; il-1r; IL1RA; IL-1RA; IL1-RA; IL-1ra3; IL-1R-alpha; IL1RN; IL-1RN; IL1RN (IL1F3); interleukin 1 receptor antagonist; interleukin-1 receptor; interleukin-1 receptor antagonist; interleukin-1 receptor antagonist protein; interleukin-1 receptor antagonist secretory form; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); IRAP; IRAP1; MGC10430; MVCD4; P80; type II interleukin-1 receptor antagonist
Gene Symbols IL1RN
Host Species Mouse
Immunogen Recombinant peptide corresponding to the extracellular domain of human CD121a expressed in insect cell line Sf21.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3557
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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