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Invitrogen™ IL1RAPL1 Polyclonal Antibody
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Catalog No. PIPA596244
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100 μL
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PIPA596244 100 μL
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Catalog No. PIPA596244 Supplier Invitrogen™ Supplier No. PA596244
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SISLTVGEND TGLCYNSKMK YFEKAELSKS KEISCRDIED FLLPTREPEI LWYKECRTKT WRPSIVFKRD TLLIREVRED D; Positive Samples: A-431, Mouse brain, Mouse heart, Rat brain, Rat heart; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Single-pass type I membrane protein, axon, dendrite.

The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signaling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL1RAPL1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.07 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Il1rapl1
Gene Accession No. P59823, P59824, Q9NZN1
Gene Alias 6330532G10Rik; C030039N24; IL1R8; Il1rapl; Il1rapl1; IL-1-RAPL-1; IL-1RAPL-1; IL1RAPL-1; interleukin 1 receptor accessory protein like 1; interleukin 1 receptor accessory protein-like 1; interleukin 1 receptor-8; interleukin-1 receptor accessory protein-like 1; mental retardation, X-linked 10; MRX10; MRX21; MRX34; Oligophrenin-4; OPHN4; Three immunoglobulin domain-containing IL-1 receptor-related 2; TIGIRR-2; X-linked interleukin-1 receptor accessory protein-like 1
Gene Symbols Il1rapl1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 130-210 of human IL1RAPL1 (NP_0550861).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11141, 317553, 331461
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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