IL2 Mouse anti-Human, Clone: OTI2C9, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF810724

Catalog No. 50-167-0278

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

Specifications

• Antigen: IL2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: IL2
• Gene Alias: IL-2, TCGF, lymphokine
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3558
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2C9
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P60568
• Gene Symbols: IL2
• Immunogen: Human recombit protein fragment corresponding to amino acids 21-153 of human IL2 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b