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IL23R Mouse anti-Human, Clone: OTI5C4, liquid, TrueMAB™
SDP

Catalog No. 501681529
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100 μL
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Catalog No. Quantity
50-168-1529 100 μL
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Catalog No. 50-168-1529 Supplier OriGene Supplier No. TA807388
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Description

Mouse Monoclonal Antibody

IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling. Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing results in six spliced isoforms of IL-23R. Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease.

Specifications

Antigen IL23R
Applications Western Blot
Classification Monoclonal
Clone OTI5C4
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene IL23R
Gene Accession No. Q5VWK5
Gene Alias interleukin 23 receptor
Gene Symbols IL23R
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 57-355 of human IL23R produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 149233
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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